DPC Doctors in South Carolina

23 Direct Primary Care practices identified in South Carolina. Find affordable, transparent primary care near you.

Browse by City

Mt Pleasant(3)Charleston(2)Rock Hill(2)Greenville(2)Spartanburg(2)Fort Mill(1)Greer(1)Murrells Inlet(1)Columbia(1)Lexington(1)Bluffton(1)Anderson(1)Easley(1)Duncan(1)Aiken(1)North Charleston(1)Mauldin(1)

New South Family Medicine

Dr. Jessica Mendelsohn, MD · Fort Mill, SC

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Accepting patientsHSA accepted

Lowcountry Wellness Center

Dr. Penni Vachon, DNP, APRN, ANP-BC · Charleston, SC

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Accepting patientsHSA accepted

Rock Hill Primary Care

Dr. Brandon Sick, MD · Rock Hill, SC

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Accepting patientsHSA accepted

Galen Healthcare

Dr. Daniel Tran, MD · Greer, SC

Accepting patientsHSA accepted

Carolina Holistic Medicine

Dr. Yusuf Saleeby, MD · Murrells Inlet, SC

Accepting patientsHSA accepted

Carolina Holistic Medicine

Dr. Yusuf Saleeby, MD · Mt Pleasant, SC

Accepting patientsHSA accepted

Palmetto Proactive Healthcare

Dr. Jerome Aya-ay, MD · Greenville, SC

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Accepting patientsHSA accepted

Palmetto Proactive Healthcare

Dr. Jennifer Mitchell, NP · Columbia, SC

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Accepting patientsHSA accepted

Palmetto Proactive Healthcare

Dr. Christopher McCarthy, MD · Spartanburg, SC

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Accepting patientsHSA accepted

Living Well Family Medicine

Dr. Dee Carter, MD · Lexington, SC

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Accepting patientsHSA accepted

LAURA C KNOBEL MD LLC

Dr. Laura Knobel, MD · Bluffton, SC

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Accepting patientsHSA accepted

Call Me MD

Dr. Frank Cioppettini, MD · Greenville, SC

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Accepting patientsHSA accepted

Direct Access

Dr. Jerry Purcell, MD · Anderson, SC

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Pennington Primary Care

Rock Hill, SC

Verity Primary Medicine & Lifestyle

Easley, SC

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Proactive MD - Duncan SC

Dr. Sandra Luyindula, MD · Duncan, SC

Proactive MD - Aiken SC

Dr. Michelle Tran, DO · Aiken, SC

Proactive MD - Spartanburg SC

Dr. Darby Darley, NP · Spartanburg, SC

Paladina Health

Mt Pleasant, SC

Paladina Health

North Charleston, SC

Access Healthcare

Dr. David Albenberg, MD · Charleston, SC

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Accepting patientsHSA accepted

Atlas Charleston

Dr. Tim Wingo, MD · Mt Pleasant, SC

Proactive MD - Mauldin, SC

Dr. Mark Kemble, MD · Mauldin, SC

Accepting patientsHSA accepted

Direct Primary Care in South Carolina

South Carolina has 23 Direct Primary Care practices across 17 cities, with monthly membership fees ranging from $10 to $100. DPC is an innovative healthcare model where patients pay a simple monthly fee for unlimited access to their primary care physician — no insurance required, no copays, and no surprise bills.

As of January 2026, DPC memberships are now eligible HSA (Health Savings Account) expenses, making it even more affordable to choose direct primary care in South Carolina. Learn how to use your HSA for DPC.

Top DPC Cities in South Carolina

DPC Doctors in Mt Pleasant3 practices DPC Doctors in Charleston2 practices DPC Doctors in Rock Hill2 practices DPC Doctors in Greenville2 practices DPC Doctors in Spartanburg2 practices

Average DPC Cost in South Carolina

$10/mo

Lowest price

$52/mo

Average price

$100/mo

Highest price

Based on 12 practices with published pricing in South Carolina. Learn more about DPC costs.

Why Choose DPC in South Carolina?

Transparent pricing — No surprise bills or hidden fees
Same-day appointments — Most DPC practices offer same-day or next-day visits
More time with your doctor — Appointments typically last 30-60 minutes
24/7 access — Many practices offer phone, text, or video access to your doctor
HSA compatible — Use tax-free HSA funds for your DPC membership

Learn More About DPC

What is Direct Primary Care?DPC Cost Guide Using HSA for DPC DPC vs. Concierge Medicine DPC vs. Traditional Insurance Frequently Asked Questions